After centuries of antagonism and misunderstanding, the Japanese finally welcome youkai into their community. In an attempt at species integration, normal children begin attending school with paranormal creatures who are quite humanoid. Shingo Ohashi finds himself developing feelings for Hatoko "Petoko" Fujimura, a half-youkai half-human girl whose powers are: uncontrollable cuteness to enchant those around her (similar to a low-power succubus), get stuck to any other person who touches her bare flesh (cured by her falling asleep), and the ability to disappear even at the molecular stage (which she can for the most part control).
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